Current:Home > ContactThe science that spawned fungal fears in HBO's 'The Last of Us' -Prime Capital Blueprint
The science that spawned fungal fears in HBO's 'The Last of Us'
View
Date:2025-04-12 19:27:46
The video game series that spawned the new hit HBO drama, The Last of Us, is the zombie genre with a twist.
Instead of a run-of-the-mill viral pandemic or bacterial disease pushing humanity to the brink, a Cordyceps fungus evolves to survive in human bodies in part due to climate change.
Fungal disease resulted in around 1.7 million deaths in 2021, but it was only last year that the World Health Organization published its first-ever list of fungal priority pathogens.
To learn more about the science that inspired The Last of Us and the real-life threats fungal researchers see in the ever-warming world, Short Wave co-host Aaron Scott recently sat down with Asiya Gusa, a post-doctoral fungal researcher at Duke University.
As a mycologist, Gusa was excited from the first scene, "When I saw the opening few minutes, I nearly jumped off the couch and was yelling at the screen, 'This is like what I study!'"
Cordyceps, the fungus in The Last of Us, does not affect humans — it affects insects. But Asiya Gusa does study one of the deadliest fungi infecting humans in the real world, Cryptococcus neoformans. The fungus is found throughout the world. Still, most who are infected do not get sick. Most infections occur in those with weakened immune systems. In those instances, the lungs and central nervous system are usually affected.
Although C. neoformans doesn't bring about zombie-like symptoms, Gusa's research does support one hypothesis from The Last of Us: As the world warms, fungi may adapt to survive. That could introduce fungi that have the ability to bypass the human body's first line of defense — its high temperature — and cause more frequent infections.
Gusa will continue her work as an assistant professor at Duke University in May. And although she spends her days immersed in fungal research, she readily admits that the field has a PR problem. Until The Last of Us, the wider public has been largely unaware of the threat they pose. She hopes the show brings lasting attention to those already suffering from fungal diseases and boosts the surveillance and research capacity for the fungi that pose real threats to humanity.
"Whenever you have something that's understudied, under-researched, and we don't have the proper tools to fight it — well, that's a cause for concern," says Gusa. "And so, you know, I don't want to sound alarm bells, but at the same time, there are already millions of people suffering from deadly fungal infections, and the attention has just not reached them."
Listen to Short Wave on Spotify, Apple Podcasts and Google Podcasts.
Curious to hear more about science in pop culture? Email us at [email protected]. You can also follow Short Wave on Twitter @NPRShortWave.
This episode was produced by Liz Metzger, edited by Rebecca Ramirez and fact-checked by Anil Oza. Josh Newell was the audio engineer.
veryGood! (4)
Related
- Trump's 'stop
- Miss Teen West Virginia Has the Perfect Bounce Back After Falling Off Stage at Competition
- Which NFL playoff teams could miss cut in 2024 season? Ranking all 14 on chances of fall
- Jobs report: Unemployment rise may mean recession, rule says, but likely not this time
- Civic engagement nonprofits say democracy needs support in between big elections. Do funders agree?
- Trump election subversion case returned to trial judge following Supreme Court opinion
- When does Simone Biles compete next? Olympic gymnastics event finals on tap in Paris
- When does the Pumpkin Spice Latte return to Starbucks? Here's what we know.
- Rolling Loud 2024: Lineup, how to stream the world's largest hip hop music festival
- Surgical castration, ‘Don’t Say Gay’ and absentee regulations. New laws go into effect in Louisiana
Ranking
- New Zealand official reverses visa refusal for US conservative influencer Candace Owens
- USA beach volleyball's perfect top tandem braves storm, delay, shows out for LeBron James
- Why Simone Biles was 'stressing' big time during gymnastics all-around final
- Every M. Night Shyamalan movie (including 'Trap'), ranked from worst to best
- Person accused of accosting Rep. Nancy Mace at Capitol pleads not guilty to assault charge
- Justin Timberlake’s License Is Suspended After DWI Arrest
- 'Bill & Ted' stars Keanu Reeves, Alex Winter to reunite in new Broadway play
- Baseball team’s charter bus catches fire in Iowa; no one is hurt
Recommendation
Meta donates $1 million to Trump’s inauguration fund
‘Taking it off the speculative market’: These nonprofits help tenants afford to stay put
Video shows fugitive wanted since 1994 being stopped for minor bicycle violation
Olympic medals today: What is the count at 2024 Paris Games on Friday?
The FBI should have done more to collect intelligence before the Capitol riot, watchdog finds
'Chronically single' TikTokers go viral for sharing horrible dating advice
Florida braces for flooding from a possible tropical storm
Increasing wind and heat plus risk of thunderstorms expected in fight against California wildfire